The new Rhino 6000 drivers for Windows 7 / 8 can be downloaded from the drivers page here:
The latest release of the Dymo Labeling Software (8.4.1) now supports Windows 8, and can be downloaded here: Windows 8 Dymo Driver
The download includes the DLS software and the appropriate Win 8 drivers. Users that have tried it so far have not reported any problems to us.
The latest Dymo Label Software for Macs now support the new Mac OS X v10.7 “Lion” operating system. You can download the software and drivers here: Dymo label Software V8 for Mac Lion